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Some Resources dedicated to Mycobacterium tuberculosis complex (MTBCtools)

Biological databases

CPLP-TB (link to publication) main goal is to facilitate exchange of molecular epidemiological data and thus enable the tracking of important MTB clones across the Lusophone space


GMTV (link to publication) integrates clinical, epidemiological and microbiological description with genome variations based on WGS data


inTB (link to publication) is a web-based system for storage and analysis of clinical, socio-demographic and molecular typing data


Mbovis.org (link to publication) hosts the Mycobacterium bovis Spoligotype Database


MtbRegList (link to publication) is a database dedicated to the analysis of transcriptional regulation in Mycobacterium tuberculosis


Mycobrowser (link to publication) is a comprehensive genomic and proteomic data repository for pathogenic mycobacteria


MycoDB.es (link to publication) is the Spanish Database of Animal Mycobacterosis


MIRU-VNTRplus (link to publication) is a web tool for polyphasic genotyping of Mycobacterium tuberculosis complex bacteria


ReSeqTB (link to publication) is a collaborative effort for a centralized worldwide TB relational sequencing data platform


SpolDB4 (link to publication) is the the fourth international spoligotyping database for MTBC classification, population genetics and epidemiology


SITVITWEB (link to publication) is the fifth international multimarker database for studying MTBC genetic diversity and molecular epidemiology


SITVIT2 (link to publication) is the sixth international multimarker database for studying MTBC genetic diversity and molecular epidemiology


tbvar (link to publication) is the Mycobacterium tuberculosis variome resource


TB database (link to publication) is an integrated platform for tuberculosis research


TB Portals (link to publication) is an open-access, web-based platform for global drug-resistant-tuberculosis data sharing and analysis


TB DEPOT (link to publication) is a multi-domain tuberculosis data analysis resource




Prediction/classification tools

CASTB (link to publication) is a total solution for epidemiological and genomic analysis of Mycobacterium tuberculosis complex


COMBAT-TB-NeoDB (link to publication) is a comprehensive bacterial analytical toolkit for TB Research (and related projects)


CRISPRbuilder-TB (link to publication) reconstructs the whole CRISPR locus from a Mycobacterium tuberculosis complex genome, by using SRA WGS data


Galru (link to publication) identifies Mycobacterium tuberculosis spoligotyping from uncorrected long reads


KvarQ (link to publication) performs targeted and direct variant calling in FastQ reads of bacterial genomes


MIRU-profiler (link to publication) performs digital 24-loci MIRU-VNTR typing for Mycobacterium tuberculosis


MIRUReader (link to publication) identifies 24-locus MIRU-VNTR for Mycobacterium tuberculosis complex directly from long reads


MixInfect (link to publication) detects mixed infections in TB


MTBseq (link to publication) is an automated pipeline for mapping, variant calling and detection of resistance mediating and phylogenetic variants from WGS TB data


PhyTB (link to publication) is a web-tool to assist phylogenetic tree visualisation and identification of M. tuberculosis clade-informative polymorphism


PolyTB (link to publication) is a genomic variation map for Mycobacterium tuberculosis


SecProMTB (link to publication) is a Support Vector Machine-Based classifier for secretory proteins using imbalanced data sets applied to Mycobacterium tuberculosis


SNP-IT (link to publication) is a Whole-genome SNP based identification tool for members of the Mycobacterium tuberculosis complex


StackTB (link to publication) is a package for classifying the lineage of Mycobacterium tuberculosis strains from MIRU-VNTR data


SpolLineages (link to publication) predicts Mycobacterium tuberculosis complex spoligotype families


SpolPred (link to publication) predicts Mycobacterium tuberculosis spoligotypes from short genomic sequences


SpolSimilaritySearch (link to publication) is a web tool allowing to search for similar spoligotyping profiles in function of a given query


SpolTools (link to publication) are online utilities for analyzing spoligotypes of the Mycobacterium tuberculosis complex


SpoTyping (link to publication) provides fast and accurate in silico Mycobacterium spoligotyping from sequence reads


TB-Lineage (link to publication) determines the major genetic lineage of a Mycobacterium tuberculosis isolate through various methods


TBminer (link to publication) predicts MTBC lineages from spoligotypes and MIRU-VNTR profiles basing on Machine Learning


TGS-TB (link to publication) provides total genotyping solution for MTB using short-read Whole Genome Sequencing


UVP (link to publication) is a unified analysis variant pipeline to identify variants and assign lineage from MTBC sequence data



Drug resistance

binoSNP (link to publication) detects low-frequency SNPs in NGS data of Mycobacterium tuberculosis complex strains


DeepAMR (link to publication) predicts co-occurrent resistance of Mycobacterium tuberculosis


MUBII-TB-DB (link to publication) is a database of mutations associated with antibiotic resistance in Mycobacterium tuberculosis


Mykrobe predictor (link to publication) predicts antibiotic-resistance from genome sequence data for S. aureus and M. tuberculosis


PhyResSE (link to publication) is a a web tool delineating Mycobacterium tuberculosis antibiotic resistance and lineage from WGS data


Resistance Sniffer (link to publication) predicts drug resistance in Mtb isolates using complete or partial genome datasets in different file formats


TBDReaMDB (link to publication) is a comprehensive database listing mutations associated with TB drug resistance


TBProfiler (link to publication) is a pipeline allowing to analyse M. tuberculosis WGS data to predict lineage and drug resistance



Other web portals

WHO provides global report and other important information on TB


E-DETECT TB (link to publication) is a research consortium for the early detection and integrated management of TB in Europe


The Union works towards the global elimination of TB


CDC provides TB reports and data for the United States of America




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